ユークロマプラスクリーム

Product details

Euchroma Plus Cream is a doctor-recommended whitening cream for treating hyperpigmentation and melasma. It is effective against blemishes and uneven skin tone caused by sun exposure, acne scars, hormonal changes, and stubborn hyperpigmentation that cannot be removed with ordinary skin creams. Dermatologists prescribe Euchroma Plus Cream, which combines hydroquinone, mometasone, and tretinoin.

By using the appropriate amount at the prescribed time as directed by your doctor, you can lighten blemishes without irritating the skin and restore a smooth, even complexion.

Pharmaceutical Information

component	Active ingredients: Hydroquinone 2% (w/w), Mometasone 0.1% (w/w), Tretinoin 0.025% (w/w)
Usage/Dosage	Apply a small amount to a clean area of ​​the affected area once a day before going to bed. Do not exceed the dosage recommended by your doctor.
Storage method	Store in a cool, dry place. Store away from direct sunlight. Keep out of reach of children and pets. Please close the tube tightly after use.

 

The effects of Euchroma Plus Cream

• It lightens melasma and dark spots caused by sun exposure.
• It improves uneven skin tone, leading to a brighter, more even complexion.
• It reduces redness and inflammation in areas of hyperpigmentation.
• With continued use, you can aim for clear, bright, and healthy-looking skin.

How to use

• Please use the medication according to your doctor's instructions, adhering to the prescribed dosage and frequency.
• Use only at night, or as directed by your doctor.
• Wash your face with a mild facial cleanser and gently pat it dry.
• Take a small amount and apply a thin layer to the areas with dark spots.
• Avoid applying to the area around the eyes, nose, and mouth.
• Please wash your hands thoroughly after use.
• This product makes your skin sensitive to sunlight, so be sure to use sunscreen during the day.

How does Euchroma Plus Cream work?

This cream works through three mechanisms.

• Hydroquinone: Suppresses melanin production, which causes skin darkening, and gradually lightens pigmented areas.
• Mometasone: Has anti-inflammatory properties that reduce skin inflammation, itching, and redness. It is particularly effective in soothing irritation and inflammation in areas with hyperpigmentation.
• Tretinoin: Promotes the turnover of dead skin cells, removing old skin and bringing new skin to the surface. This action enhances the penetration and effectiveness of the cream, leading to smoother skin.

These three effects work together to gradually lighten blemishes and dark spots, resulting in clearer, more radiant skin.

Side effects of Euchroma Plus cream

Most people can use it without any problems, but in rare cases, mild side effects may occur.

• Mild burning or stinging sensation
• Skin redness
• itching and irritation
• Dryness or mild peeling

These symptoms are mild and usually disappear as the skin adapts with continued use.
However, if symptoms worsen, discontinue use and consult a doctor.

Precautions and warnings for use

• Do not use if you have allergies to any of the ingredients.
• Do not use on injured skin, inflamed skin, or sunburned areas.
• If you are pregnant or breastfeeding, please consult your doctor before use.
• Avoid excessive sun exposure and always use sunscreen during the day.
• Avoid using this product on children under 12 years of age unless directed by a doctor.
• Please refrain from using cosmetics or harsh skincare products on the treatment area.

contraindication

The following people should not use Euchroma Plus Cream:

• People with allergies to hydroquinone, mometasone, tretinoin, or similar medications.
• People with very sensitive skin who are prone to reactions to topical treatments
• Patients with viral, fungal, or bacterial skin infections in the treatment area.

Drug interactions

If you are using any of the following products, please consult your doctor:

• Other whitening creams
• Retinoid products
• Steroid cream
• Powerful peeling agent/exfoliating agent
• Products containing salicylic acid, glycolic acid, and benzoyl peroxide.
• Using multiple ingredients together may increase skin irritation.

FAQs

Q1. Can Eukroma Plus Cream be used daily?
A.   Yes. Use it only once a day, at night, and for the duration prescribed by your doctor.

Q2. How long does it take to see results?
A.   Many people notice a change in 4 to 8 weeks, but this varies depending on skin type and the severity of symptoms.

Q3. Can I apply makeup after applying this cream?
A.   Yes, but only the following morning. Do not apply makeup over the cream at night.

Q4. Is sunscreen necessary while using this product?
A.  Yes. Sunscreen is essential. Please be sure to use it during the day to prevent further hyperpigmentation.

Q5. Can I apply it to my entire face?
A.   No. Unless instructed by a doctor, apply it only to the areas with dark spots.

Q6. Can it be used on acne scars?
A.   Yes. It is effective for hyperpigmentation from acne scars, but do not use it on active acne.

Q7. What should I do if I forget to use it?
A.  Apply one dose the following night as usual. Do not apply two doses at once.

1. Galderma Laboratories LP. TRI-LUMA (fluocinolone acetonide 0.01%, hydroquinone 4%, tretinoin 0.05%) cream: prescribing information [Internet]. Silver Spring (MD): US Food and Drug Administration; 2013 Jan [cited 2025 Dec 24]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/021112s006lbl.pdf
2. Galderma Laboratories LP. Tri-Luma Cream | Treat your melasma [Internet]. Fort Worth (TX): Galderma; [cited 2025 Dec 24]. Available from: https://www.triluma.com/.
3. Godse KV. Triple combination of hydroquinone, tretinoin and mometasone furoate with glycolic acid peels in melasma [Internet]. Indian J Dermatol. 2009;54(1):92-3. doi: 10.4103/0019-5154.49005. [cited 2025 Dec 24]. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC2800888/